Fig. 3. Cell morphology, proliferation and viability upon exposure to TiO2 NPs: (a) fibroblast and (b) keratinocyte proliferation with phase contrast images demonstrating alterations in the cell morphology. Graphs showing the percentage of viable, apoptotic and necrotic cells of fibroblasts (c) and keratinocytes (d) obtained using flow cytograms of annexin V/PI staining. (e and f) Cell cycle progression upon exposure of fibroblasts and keratinocytes to nanoparticles, respectively.
