Fig. 7. ROS assays with different doses of GEN, ICG-Gen@CasNPs, ICG, placebo CasNPs, with a 250 nM dose without NIR light (A),with NIR light exposure (B), and a 350 nM dose of GEN, ICG-Gen@CasNPs, ICG, placebo CasNPs without NIR light (C), with NIR light (D); temperature changes in response to 808 nm laser irradiation with a power density of 0.6 W cm−2 in PBS, placebo CasNPs, ICG,GEN, ICG-Gen@CasNPs (E); QPCR analysis for caspase 3, BMI-1, EZH2, AKT, mTOR with the control, ICG, GEN, placebo CasNPs, ICG-Gen@CasNPs with NIR light exposure (F).
