Table 5.

Distribution of life quality scores of the patients in Intervention 1 and Intervention 2 groups at the first and last follow-up

SGRQ sub-dimensions and total score		Groups		Test statistic p**
		Intervention 1 (n=32) $\overline{x}\pm sem$	Intervention 2 (n=35) $\overline{x}\pm sem$
Effect	First follow-up	51.89±3.27	50.04±3.1	F=0.158 p=0.693
	Second follow-up	29.47±3.67	33.5±3.5	F=0.606 p=0.440
	Test statistic p**	F=87.035 p<0.001	F=51.889 p<0.001
	*Group × time effect: F=2.989; p*=0.090; group effect: F=0.057; p=0.812; time effect: F=8.876; p=0.004
Symptom	First follow-up	65.23±2.87	63.25±2.74	F=0.232 p=0.632
	Second follow-up	60.45±2.91	60.14±2.77	F=0.006 p=0.937
	Test statistic p**	F=38.552 p<0.001	F=18.209 p<0.001
	*Group × time effect: F=2.261; p=0.139; group effect: F=0.079; p=0.779; time effect: F=6.114; p=0.017
Activity	First follow-up	72.57±2.97	70.53±2.84	F=0.233 p=0.631
	Second follow-up	56.69±3.32	56.39±3.17	F=0.004 p=0.949
	Test statistic p**	F=40.701 p<0.001	F=35.496 p<0.001
	*Group × time effect: F=0.241; p=0.626; group effect: F=0.081; p=0.777; time effect: F=17.919; p <0.001
Total	First follow-up	60.37±2.71	58.44±2.59	F=0.249 p=0.620
	Second follow-up	42.87±3.01	44.88±2.87	F=0.220 p=0.641
	Test statistic p**	F=83.798 p<0.001	F=55.362 p<0.001
	*Group × time effect: F=2.093; p=0.154; group effect: F=0.001; p=0.991; time effect: F=14.257; p <0.001

F, two-way repeated measures Anova

*Group × time effect, the comparison value between groups of the first and last follow-up differences of each group

**Adjusted for age, gender, educational status, marital status, time of diagnosis, smoking status, alcohol drinking status, hospitalization status (last 1 year), duration of hospital stay, and training status for inhaler utilization