Table 1.
The clinical characteristic of enrolled patients and health participants
| MOG-ON (n = 17, eyes = 26) |
AQP4-ON (n = 26, eyes = 40) |
HC (n = 30, eyes = 60) |
|
|---|---|---|---|
| Number of patients | 17 | 26 | 30 |
| Gender (Male / Female) | 8/9* | 2/24 | 9/21 |
| Age (years) | 34.88 (14.12) | 40.50 (11.99) | 38.62 (12.20) |
| ON history (unilateral / bilateral) | 8/9 | 12/14 | NA |
| Number of eyes | 26 | 40 | 60 |
| ON disease duration (mon, per eye) | 42.0 (6–156) | 54.0 (8–144) | NA |
| Number of ON episodes (n, per eye) | 1.35 (0.56) | 2.05 (1.84) | NA |
| Duration since last ON (mon, per eye) | 12 (6–156) | 24 (6–144) | NA |
| Visual accuracy (logMAR, per eye) | 0.33 (0.26)* | 0.66 (0.68) | NA |
| EDSS | 3.00 (1–6.5) | 3.5 (2–6.5) | NA |
AQP4 Aquaporin4-IgG seropositive, EDSS Expanded disability status scale, HC Health controls, MOGAD MOG-Ab-associated disease, ON Optical neuritis, NA Not applicable, * p＜0.05