Table 2.
Retina structural data of MOGAD-ON eyes in comparison to AQP4-Ab-ON eyes and HC
| MOG-ON | AQP4-ON | HC | MOG-ON VS. AQP4-ON | MOG-ON VS. HC | |||||
|---|---|---|---|---|---|---|---|---|---|
| Eye = 26 | Eye = 40 | Eye = 60 | B | SE | p | B | SE | p | |
| pRNFL (um) | 75.49 (17.98) | 78.69 (18.59) | 119.74 (10.08) | −0.015 | 0.016 | 0.350 | −0.238 | 0.071 | 0.001* |
| TEM-RNFL (um) | 49.80 (16.90) | 55.37 (14.78) | 84.03 (9.38) | −0.020 | 0.019 | 0.310 | −0.163 | 0.039 | 0.000* |
| SUP-RNFL (um) | 92.84 (24.56) | 96.56 (29.42) | 146.31 (14.71) | −0.010 | 0.010 | 0.317 | −0.305 | 0.117 | 0.009* |
| NAS-RNFL (um) | 65.48 (14.25) | 64.88 (14.25) | 96.03 (15.68) | −0.003 | 0.019 | 0.857 | −0.134 | 0.031 | 0.000* |
| INF-RNFL (um) | 93.01 (28.18) | 97.79 (29.26) | 152.58 (17.51) | −0.008 | 0.010 | 0.392 | −0.103 | 0.025 | 0.000* |
| GCC (um) | 74.71 (10.19) | 74.28 (13.70) | 99.12 (5.07) | −0.013 | 0.022 | 0.555 | −0.029 | 0.018 | 0.000* |
| Outer Retina (um) | 172.21 (6.63) | 175.67 (8.82) | 175.62 (7.55) | −0.058 | 0.039 | 0.137 | −0.184 | 0.029 | 0.062 |
AQP4-ON Aquaporin4-IgG seropositive optical neuritis, B Beta, GCC Ganglion cell complex, also refer to the inner retina, HC Health controls, INF Inferior quadrant, MOGAD-ON MOG-Ab-associated disease optical neuritis, NAS Nasal quadrant, pRNFL peri-papillary retinal nerve fiber layer, SUP Superior quadrant, SE Standard error, TEM Temporal quadrant, * p＜0.05