Table 3.
Retina angiography data of MOGAD-ON eyes in comparison to AQP4-Ab-ON eyes and health controls
| MOG-ON | AQP4-ON | HC | MOG-ON VS. AQP4-ON | MOG-ON VS. HC | |||||
|---|---|---|---|---|---|---|---|---|---|
| Eye = 26 | Eye = 40 | Eye = 60 | B | SE | p | B | SE | p | |
| Optic disk RPC (%) | 49.53 (4.87) | 49.14 (6.42) | 55.35 (3.82) | −0.072 | 0.051 | 0.154 | −0.288 | 0.069 | 0.000* |
| Capillary RPC (%) | 52.74 (5.98) | 48.63 (7.51) | 51.14 (2.13) | −0.058 | 0.046 | 0.203 | −0.808 | 0.194 | 0.000* |
| Superficial retina VD | |||||||||
| Whole VD (%) | 44.22 (4.69) | 46.01 (6.31) | 51.99 (2.88) | −0.041 | 0.041 | 0.320 | −0.560 | 0.122 | 0.000* |
| Fovea (%) | 13.16 (6.43) | 15.31 (6.02) | 19.91 (6.60) | −0.045 | 0.045 | 0.310 | −0.168 | 0.452 | 0.000* |
| para-TEM (%) | 46.13 (5.55) | 48.27 (6.56) | 53.31 (3.38) | −0.029 | 0.039 | 0.462 | −0.323 | 0.074 | 0.000* |
| para-SUP (%) | 47.93 (6.07) | 49.26 (6.77) | 54.53 (4.02) | −0.039 | 0.043 | 0.366 | −0.263 | 0.065 | 0.000* |
| para-NAS (%) | 44.64 (6.16) | 47.93 (6.57) | 52.83 (3.86) | −0.090 | 0.044 | 0.040* | −0.315 | 0.073 | 0.000* |
| para-INF (%) | 45.22 (6.73) | 47.87 (6.84) | 53.43 (4.76) | −0.066 | 0.042 | 0.110 | −0.231 | 0.054 | 0.000* |
| peri-TEM (%) | 42.54 (3.56) | 44.30 (5.56) | 48.40 (2.77) | −0.097 | 0.058 | 0.094 | −0.498 | 0.103 | 0.000* |
| peri-SUP (%) | 45.01 (5.18) | 46.54 (7.39) | 53.09 (2.98) | −0.043 | 0.428 | 0.313 | −0.511 | 0.116 | 0.000* |
| peri-NAS (%) | 46.73 (6.0)1 | 48.92 (6.83) | 55.89 (2.77) | −0.059 | 0.436 | 0.173 | −0.507 | 0.112 | 0.000* |
| peri-INF (%) | 44.41 (6.07) | 46.27 (7.34) | 52.53 (3.17) | −0.053 | 0.417 | 0.207 | −0.402 | 0.091 | 0.000* |
| Deep retina VD | |||||||||
| Whole VD (%) | 48.01 (7.58) | 52.61 (6.72) | 54.84 (5.41) | −0.091 | 0.040 | 0.022* | −0.163 | 0.045 | 0.000* |
| Fovea (%) | 29.28 (7.03) | 31.99 (6.88) | 37.12 (8.06) | −0.046 | 0.041 | 0.259 | −0.123 | 0.036 | 0.001* |
| para-TEM (%) | 54.38 (8.16) | 57.78 (4.84) | 59.57 (3.72) | −0.086 | 0.050 | 0.087 | −0.192 | 0.062 | 0.002* |
| para-SUP (%) | 53.75 (7.39) | 57.73 (5.19) | 58.25 (4.35) | −1.488 | 1.532 | 0.044* | −0.137 | 0.048 | 0.004* |
| para-NAS (%) | 53.75 (8.18) | 57.64 (5.69) | 59.47 (4.24) | −0.107 | 0.049 | 0.029* | −0.172 | 0.053 | 0.001* |
| para-INF (%) | 50.77 (8.44) | 56.03 (5.98) | 57.38 (5.32) | −0.101 | 0.042 | 0.016* | −0.142 | 0.042 | 0.001* |
| peri-TEM (%) | 51.52 (6.90) | 54.68 (6.76) | 57.86 (4.86) | −0.073 | 0.039 | 0.062 | −0.197 | 0.052 | 0.000* |
| peri-SUP (%) | 48.12 (9.65) | 53.18 (8.12) | 56.40 (6.65) | −0.063 | 0.032 | 0.052 | −0.129 | 0.038 | 0.001* |
| peri-NAS (%) | 47.18 (9.17) | 54.19 (7.45) | 55.01 (6.50) | −0.098 | 0.035 | 0.005* | −0.130 | 0.037 | 0.000* |
| peri-INF (%) | 47.58 (8.55) | 52.86 (8.09) | 55.21 (6.70) | −0.073 | 0.033 | 0.028* | −0.125 | 0.036 | 0.000* |
AQP4-ON Aquaporin4-IgG seropositive optical neuritis, B Beta, GCC Ganglion cell complex, HC Health controls, INF Inferior quadrant, MOGAD-ON MOG-Ab-associated disease optical neuritis, NAS Nasal quadrant, pRNFL peri-papillary retinal nerve fiber layer, RPC radial peripapillary capillaries, SUP Superior quadrant, SE Standard error, TEM Temporal quadrant, VD Vessel densities, * p＜0.05