Fig. 5.

Representative imaging of patients with only ¹⁸F-FES-positive lesions. A Low FES-HI (Fig. 2, #10). This 67-year-old woman had 2 ¹⁸F-FES-positive lesions in the chest wall and lung, with no ¹⁸F-FES-negative lesions. The median FES-HI for the 2 avid lesions was 1.38. She was on palbociclib combined with letrozole as first-line treatment for 30.4 months without disease progression. B High FES-HI (Fig. 2, #32). This 56-year-old woman had 6 ¹⁸F-FES-positive lesions in the lymph nodes, with no ¹⁸F-FES-negative lesions. The median FES-HI for the 6 avid lesions was 1.52. She was on palbociclib combined with fulvestrant as first-line treatment for 16.5 months until progression