Table 5.

Risk factors associated with the development of a first liver-related event during the pandemic period amongst people with NAFLD cirrhosis without prior decompensations.

	Univariate regression			Multivariable regression
	OR	95% CI	p value	OR	95% CI	p value
Age	0.99	0.92-1.08	0.96
Female sex	3.21	0.82-1.03	0.09	0.49	0.19-1.23	0.13
Arterial hypertension	1.03	0.28-3.74	0.95
T2D	0.10	0.01-0.52	0.007	3.77	1.15-12.32	0.028
Dyslipidaemia	1.95	0.67-6.17	0.25
Metabolic status worsening	2.65	0.78-8.88	0.11
BMI	0.92	0.82-1.03	0.16
Creatinine	1.88	0.12-28.77	0.64
Albumin∗	0.21	0.06-0.73	0.014	4.43	1.76-11.17	0.002
Bilirubin	0.62	0.13-2.86	0.54
MELD score	0.87	0.61-1.24	0.46
FIB-4 score∗∗	1.49	1.18-1.89	0.001	15.74	2.01-123.22	0.009

Results from univariate and multivariable regression analysis. A p <0.05 was considered statistically significant.

MELD, model for end-stage liver disease; NAFLD, non-alcoholic fatty liver disease; OR, odds ratio; T2D, type 2 diabetes.

^∗Albumin cut-off <4.0 g/dl.

^∗∗FIB-4 score cut-off >2.67.