Fig. 2. Effects of the carbon dots upon hIAPP fibrillation. (A) ThT fluorescence curves. (i) hIAPP alone (black curve); hIAPP + Tyr-C-dots (blue); hIAPP + Phe-C-dots (red). (ii) hIAPP alone (solid curve), hIAPP + Tyr-C-dots (0.01 mg mL−1; short dash), hIAPP + Phe-C-dots (0.03 mg mL−1; long dash). (B) Transmission electron microscopy (TEM) images. Bars correspond to 100 nm. (C) Circular dichroism (CD) spectra. In all panels: turquoise spectra were recorded immediately after peptide and C-dots dissolution in PB buffer; orange spectra: 6 hours after dissolution; purple spectra: 24 hours after dissolution.
