Scheme 1. Experimental concept. Monomeric hIAPP (blue peptide, left) undergoes spontaneous assembly in buffer, forming amyloid fibrils (shown schematically on the right). We examine how co-incubating hIAPP with C-dots (red spheres) prepared from either citric acid and phenylalanine as the carbon precursors (top-A) or citric acid and tyrosine (bottom-B) might affect the fibrillation process.
