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. 2022 Aug 27;14:107. doi: 10.1186/s13148-022-01323-6

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© The Author(s) 2022

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 3 — The MinION sequencing device—DNA sequencing is performed by adding a sample to the flow cell. The sensor measures the change in magnitude of current in the nanopore when the DNA molecule passes through it. The data streams are passed to the application-specific integrated circuit ASIC and MinKnow, which generate the signal-level data. Image reprinted from [63] with permission of the publisher (Request ID 600062077, 01 Dec 2021)