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. 2022 Aug 28;104(4):115803. doi: 10.1016/j.diagmicrobio.2022.115803

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Fig 2 — Imbalanced anti-S1 and anti-N antibody levels among naturally infected individuals. Anti-N and anti-S1 antibody levels within the same individual obtained using the Bioplex multiplex assay were compared. Most individuals developed both anti-S1 and anti-N antibodies after natural infection. Among them, 43.2% (19 of 44) in the recovery cohort showed a higher level of anti-S1 than anti-N antibodies. Anti-S1/anti-N ratio ranging from 0.07 to 16.26 with median = 0.62. In the active infection group, 52.0% (13 of 25) showed a higher level of anti-S1 than anti-N antibodies. Anti-S1/anti-N ratio ranging from 0.05 to 53.74 with median = 0.80. Between the recovery and active infection group, no significant difference was observed in anti-N antibody levels, anti-S1 antibody levels, or anti-S1/anti-N antibody ratio (P > 0.05).