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. 2022 Aug 27;13:5047. doi: 10.1038/s41467-022-32626-0

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 3 — a GT (cyan) and DeepSTORM (DS) predicted images (magenta) of a TOM20-labelled structure recorded for imager strand concentrations of 0.5, 5, 10, and 20 nM. b Structure map with Pearson correlation coefficients (PCC) indicating either regions of good overlap between GT and predicted image (yellow structures; yellow arrow), denser GT structures (cyan structures; white arrow) or denser DeepSTORM predicted structures (magenta structures; magenta arrow). c Sharpening map indicating regions of artificial sharpening with the same colour scheme as the structure map. d Confidence map highlighting structures of high confidence (cyan) and low confidence (red). b, c, d; first column) Schematic explaining HAWKMAN maps. HAWKMAN applied to n = 1 ROI (a–d); scale bars: 1 µm.