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. 2022 Aug 27;13:5047. doi: 10.1038/s41467-022-32626-0

Fig. 4. Resolving synaptic active zone nanostructures Bassoon and Homer using DeepSTORM.

Fig. 4

a Comparison of two images of presynaptic Bassoon (cyan) and postsynaptic Homer (red) scaffold proteins in the active zone of neurons between ground truth (GT; 0.5 nM, 10,000 frames, 25 min; yellow Picasso icon) and predicted images (5 nM, 800 frames; 2 min; DeepSTORM icon). b The cluster area of single Bassoon structures of GT plotted against DeepSTORM predicted clusters to quantify structural similarity and reconstruction; slope = 91 and Pearson’s r = 0.99; n = 75 clusters from 3 tissue samples. Scale bars: 0.2 µm. Source data are provided as a Source Data file.