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. 2022 Aug 27;6:38. doi: 10.1038/s41538-022-00156-0

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — a Changes in the body weight of rats over 11 weeks. At week 11, multiple obesity-related parameters were recorded for the five groups of rats receiving HFD, HFD + low-dose stigmasterol (STL), HFD + high-dose stigmasterol (STH), HFD + simvastatin group (SIM), control diet (CON), respectively. The parameters of rats included: b viseral fat weight; c liver weight; d serum levels of lipid (TC, TG, LDL-C, HDL-C/TC); e serum levels of liver function (AST and ALT); f H&E staining and ORO staining of liver, Scale bar: 50 μm. Data are expressed as mean ± standard deviation. n = 8. One-way ANOVA was used to analyze statistical differences; compared with control group, ^#P < 0.05, ^##P < 0.01; compared with HFD group, ^*P < 0.05, ^**P < 0.01.