Figure 2. Effects of applied extracts on pro-oxidant parameters: (A) hydrogen peroxide (H2O2); (B) nitrites (NO-2); (C) index of lipid peroxidation (TBARS). E150, E1100, and E1200: Rats treated with 50, 100, and 200 mg/kg of Melissa officinalis ethanolic (70%) macerate; E250, E2100, and E2200: Rats treated with 50, 100, and 200 mg/kg of M. officinalis aqueous extract obtained under reflux of solvent; E350, E3100, and E3200: Rats treated with 50, 100, and 200 mg/kg of M. officinalis ethanolic (70%) extract obtained under reflux of solvent; a, Significant differences compared to the control group at the level of P < 0.05; b, Significant differences compared to indomethacin (IND) group at the level of P < 0.05. Data are expressed as means ± standard deviation (SD).
