Table 2.

Comparison of symptoms and signs of MGD patients between different subgroups

	SPEED Median (IQR)	TBUT M (IQR)	CFSS M (IQR)	MGYSS M (IQR)	a n (%)	b n (%)	c n (%)	d n (%)	e n (%)
Total (n = 122)	14.00(11.75–18.00)	2.77(2.20–3.99)	1.25(0.00–2.00)	4.50(2.50–7.5)	93(76.2)	40(32.8)	40(32.8)	30(24.6)	44(36.1)
Age
< 40 years (n = 61)	14.00(12.00–18.00)	2.71(2.19–4.05)	1.50(0.00–2.25)	4.50(2.25–7.50)	43(70.5)	8(13.1)	5(8.2)	4(6.6)	15(24.6)
≥ 40 years (n = 61)	14.00(11.00–18.00)	2.84(2.26–3.82)	1.00(0.00–2.00)	5.00(2.50–7.75)	50(82.0)	32(52.5)	35(57.4)	26(42.6)	29(47.5)
p	0.463	0.794	0.422	0.424	0.201	<0.0001*	<0.0001*	<0.0001*	0.014*
sex
Male (n = 27)	13.00(11.00–18.00)	3.14(2.62–4.23)	1.00(0.00–2.00)	5.00(2.50–9.00)	22(81.5)	8(29.6)	11(40.7)	7(25.9)	10(37.0)
Female (n = 95)	14.00(12.00–18.00)	2.68(2.14–3.80)	1.50(0.50–2.00)	4.50(2.50–6.50)	71(74.7)	32(33.7)	29(30.5)	23(24.2)	34(35.8)
p	0.736	0.059	0.176	0.302	0.611	0.818	0.357	1.000	1.000
Menopause
No (n = 71)	14.00(12.00–18.00)	2.72(2.22–3.93)	1.50(0.50–2.00)	4.50(2.00–7.00)	49(69.0)	16(22.5)	13(18.3)	11(15.5)	20(28.2)
Yes (n = 24)	13.50(8.25–18.75)	2.62(2.00–3.42)	1.25(0.00–2.88)	4.75(2.63–6.50)	22(91.7)	16(66.7)	16(66.7)	12(50.0)	14(58.3)
p	0.210	0.555	0.979	0.559	0.031*	< 0.0001*	< 0.0001*	0.002*	0.013*
Region
North (n = 69)	15.00(12.00–19.00)	2.77(2.12–4.05)	1.00(0.00–2.00)	4.50(1.50–7.00)	65(94.2)	36(52.2)	37(53.6)	28(40.6)	32(46.4)
South (n = 53)	14.00(11.00–17.00)	2.78(2.35–3.67)	1.50(0.00–2.25)	4.50(3.00–7.75)	28(52.8)	4(7.5)	3(5.7)	2(3.8)	12(22.6)
p	0.173	0.895	0.365	0.221	< 0.0001*	< 0.0001*	< 0.0001*	< 0.0001*	0.008*

SPEED Standard patient evaluation of eye dryness, TBUT Tear break-up time, CFSS Corneal fluorescein staining score, MGYSS Meibomian gland yielding secretion score

a: Lid margin hyperemia, b: Lid margin thickening, c: Lid margin rounding, d: Hyperkeratinization, e: Telangiectasia around orifices

^* p < 0.05