Table 4.
Results of the multivariable cause-specific Cox model studying the associations between the percentage of CD28-CD8+ T cells and graft survival.
| HR | 95% CI | p-value | |
|---|---|---|---|
| Log of CD28-CD8+ T cells (%) | 1.15 | [0.88; 1.51] | 0.2963 |
| Male recipient | 1.57 | [0.84; 2.94] | 0.1605 |
| Retransplantation | 1.14 | [0.48; 2.70] | 0.7731 |
| DGF | 1.17 | [0.66; 2.09] | 0.5954 |
| Cold ischemia time (hours) | 0.0548 | ||
| Between 12 and 24 h (vs. less than 12 h) | 3.76 | [1.15; 12.31] | |
| 24 h or more (vs. less than 12 h) | 2.34 | [0.58; 9.49] | |
| History of hypertension | 0.68 | [0.31; 1.48] | 0.3267 |
| Donor older than 55 years | 0.97 | [0.55; 1.71] | 0.9077 |
| HLA-A-B-DR mismatches > 4 | 1.92 | [1.01; 3.62] | 0.0453 |
| CSA | 1.98 | [0.79; 4.97] | 0.1451 |
| Positive anti-class II immunization | 1.60 | [0.82; 3.10] | 0.1683 |
| Creatininemia at biopsy (µmol/l) | 1.02 | [1.01; 1.02] | <0.0001 |
CI, confidence interval; CSA, cyclosporin A; DGF, delayed graft function; HLA, human leucocyte antigens; HR, hazard ratio; Log: natural logarithm.