Table 5.
Results of the multivariable cause-specific Cox model studying the associations between the absolute number of CD28-CD8+ T cells and graft survival.
| HR | 95% CI | p-value | |
|---|---|---|---|
| Log of CD28-CD8+ T cells (absolute value) | 1.17 | [0.93; 1.46] | 0.1791 |
| Male recipient | 1.55 | [0.82; 2.90] | 0.1742 |
| Retransplantation | 1.20 | [0.51; 2.83] | 0.6730 |
| DGF | 1.16 | [0.65; 2.08] | 0.6128 |
| Cold ischemia time (hours) | 0.0536 | ||
| Between 12 and 24 h (vs. less than 12 h) | 3.76 | [1.15; 12.31] | |
| 24 h or more (vs. less than 12 h) | 2.32 | [0.57; 9.42] | |
| History of hypertension | 0.67 | [0.31; 1.47] | 0.3201 |
| Donor older than 55 years | 0.95 | [0.54; 1.69] | 0.8692 |
| HLA-A-B-DR mismatches > 4 | 1.86 | [0.99; 3.52] | 0.0555 |
| CSA | 1.97 | [0.79; 4.95] | 0.1483 |
| Positive anti-class II immunization | 1.61 | [0.83; 3.14] | 0.1617 |
| Creatininemia at biopsy (µmol/l) | 1.02 | [1.01; 1.02] | <0.0001 |
CI, confidence interval; CSA, cyclosporin A; DGF, delayed graft function; HLA, human leucocyte antigens; HR, hazard ratio; Log: natural logarithm.