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. 2022 Aug 15;13:931756. doi: 10.3389/fendo.2022.931756

Table 1.

Baseline characteristics of total stimulation cycles after matching.

GROUP 1. r-hFSH + hMG GROUP 2. r-hFSH + r-hLH P-value
Stimulation cycle n=311 n=192
Age (year) 36.05 ± 3.56 35.48 ± 3.90 0.099
BMI (kg/m2) 22.48 ± 3.51 22.30 ± 3.15 0.562
AMH (ng/mL) 3.53 ± 3.49 3.77 ± 3.51 0.448
Infertility history 0.801
Primary 186 (59.81%) 117 (60.94%)
Secondary 125 (40.19%) 75 (39.06%)
Causes of infertility 0.343
Uterine factor 89 (28.62%) 40 (20.83%)
Ovarian factor 81 (26.05%) 47 (24.48%)
Tubal factor 29 (9.32%) 24 (12.50%)
Male factor 26 (8.36%) 22 (11.46%)
Mix factor 23 (7.40%) 16 (8.33%)
Others 63 (20.26%) 43 (22.40%)
Basal FSH (mIU/mL) 7.13 ± 3.16 7.35 ± 3.67 0.485
Basal LH (mIU/mL) 3.88 ± 2.06 4.58 ± 4.19 0.034*
Total FSH dose (IU) 3362.45 ± 1072.79 2602.15 ± 930.26 <0.001*
Total LH dose (IU) 1152.01 ± 608.85 947.66 ± 510.60 <0.001*
FSH/LH dose ratio 4.12 ± 4.18 4.05 ± 3.85 0.843
Induce days 10.22 ± 1.83 9.80 ± 1.31 0.003*
Oral agents (used) @ 5 (1.61%) 5 (2.60%) 0.437
Growth hormone (used) 13 (4.18%) 6 (3.13%) 0.547
Trigger type # 0.001*
Dual trigger a 272 (87.46%) 153 (79.69%)
GnRH-agonist b 17 (5.47%) 27 (14.06%)
r-hCG c 15 (4.82%) 12 (6.25%)
Others 7 (2.25%) 0 (0.00%)
Procedure $ 0.411
IVF d 203 (65.27%) 117 (60.94%)
ICSI e 88 (28.30%) 56 (29.17%)
IVF+ICSI 14 (4.50%) 11 (5.73%)
TESE-ICSI f 6 (1.93%) 8 (4.17%)

*Statistical significance. Values are presented in mean ± standard deviation or number (percentage). @ Oral agents: Letrozole or Clomiphene # a) Dual trigger = Ovidrel 250 μg + Decapeptyl 0.2 mg; b) GnRH-agonist = Decapeptyl 0.2 mg; c) r-hCG = Ovidrel 500 μg $ d) IVF: in vitro fertilization; e) ICSI: Intracytoplasmic Sperm Injection; f) TESE: Testicular Sperm Extraction