Table 1.
GROUP 1. r-hFSH + hMG | GROUP 2. r-hFSH + r-hLH | P-value | |
---|---|---|---|
Stimulation cycle | n=311 | n=192 | |
Age (year) | 36.05 ± 3.56 | 35.48 ± 3.90 | 0.099 |
BMI (kg/m2) | 22.48 ± 3.51 | 22.30 ± 3.15 | 0.562 |
AMH (ng/mL) | 3.53 ± 3.49 | 3.77 ± 3.51 | 0.448 |
Infertility history | 0.801 | ||
Primary | 186 (59.81%) | 117 (60.94%) | |
Secondary | 125 (40.19%) | 75 (39.06%) | |
Causes of infertility | 0.343 | ||
Uterine factor | 89 (28.62%) | 40 (20.83%) | |
Ovarian factor | 81 (26.05%) | 47 (24.48%) | |
Tubal factor | 29 (9.32%) | 24 (12.50%) | |
Male factor | 26 (8.36%) | 22 (11.46%) | |
Mix factor | 23 (7.40%) | 16 (8.33%) | |
Others | 63 (20.26%) | 43 (22.40%) | |
Basal FSH (mIU/mL) | 7.13 ± 3.16 | 7.35 ± 3.67 | 0.485 |
Basal LH (mIU/mL) | 3.88 ± 2.06 | 4.58 ± 4.19 | 0.034* |
Total FSH dose (IU) | 3362.45 ± 1072.79 | 2602.15 ± 930.26 | <0.001* |
Total LH dose (IU) | 1152.01 ± 608.85 | 947.66 ± 510.60 | <0.001* |
FSH/LH dose ratio | 4.12 ± 4.18 | 4.05 ± 3.85 | 0.843 |
Induce days | 10.22 ± 1.83 | 9.80 ± 1.31 | 0.003* |
Oral agents (used) @ | 5 (1.61%) | 5 (2.60%) | 0.437 |
Growth hormone (used) | 13 (4.18%) | 6 (3.13%) | 0.547 |
Trigger type # | 0.001* | ||
Dual trigger a | 272 (87.46%) | 153 (79.69%) | |
GnRH-agonist b | 17 (5.47%) | 27 (14.06%) | |
r-hCG c | 15 (4.82%) | 12 (6.25%) | |
Others | 7 (2.25%) | 0 (0.00%) | |
Procedure $ | 0.411 | ||
IVF d | 203 (65.27%) | 117 (60.94%) | |
ICSI e | 88 (28.30%) | 56 (29.17%) | |
IVF+ICSI | 14 (4.50%) | 11 (5.73%) | |
TESE-ICSI f | 6 (1.93%) | 8 (4.17%) |
*Statistical significance. Values are presented in mean ± standard deviation or number (percentage). @ Oral agents: Letrozole or Clomiphene # a) Dual trigger = Ovidrel 250 μg + Decapeptyl 0.2 mg; b) GnRH-agonist = Decapeptyl 0.2 mg; c) r-hCG = Ovidrel 500 μg $ d) IVF: in vitro fertilization; e) ICSI: Intracytoplasmic Sperm Injection; f) TESE: Testicular Sperm Extraction