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. 2022 Aug 24;15:4873–4890. doi: 10.2147/JIR.S369690

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© 2022 Nie et al.

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Time course of SPP1/TIMP1/AnxA1 mRNA expression in the ischemic penumbra of rats after MCAO/R. (A) SPP1, (B) TIMP1, (C) AnxA1. Mean ± SEM, n = 6, ^##p < 0.01, ^####p < 0.0001, vs Sham group. *p < 0.05, ****p < 0.0001, vs MCAO/R 24h group.