Table 1.

Summary of volumetric predictors of treatment outcome.

Region	Baseline	Longitudinal Changes
Hippocampus	Strong evidence for association between larger hippocampal volume and positive treatment outcome, effect localized to body/tail, mixed results for lateralization	Moderate evidence for association between increases in hippocampal volume and positive treatment outcome, left lateralization, various time scales.
Amygdala	None reported despite targeted investigations	None reported
ACC	Moderate evidence for association between larger ACC volume and positive treatment outcome	None reported
CSF	Weak evidence for association between smaller CSF volume and positive treatment outcome	None reported
Middle frontal gyrus	Weak evidence for association between larger hippocampal volume and positive treatment outcome	None reported
Whole-brain	No association with treatment outcome	None reported