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. 2022 Aug 17;36:103157. doi: 10.1016/j.nicl.2022.103157

Table 5.

Summary of task activation predictors of treatment outcome.

Region Baseline Association Treatment Longitudinal Changes with Treatment
Amygdala Strong evidence for association between lower amygdala activation and positive treatment outcome in emotional tasks with negative stimuli Moderate evidence for association between decreased amygdala activation and positive treatment outcome in emotional tasks with negative stimuli
subgenual ACC Weak evidence for association between higher sgACC activation and positive treatment outcome in emotional tasks with negative stimuli None reported
pregenual ACC Moderate evidence for association between higher pgACC activation and positive treatment outcome in emotional tasks with negative stimuli and cognitive tasks None reported
dorsal ACC Weak evidence for association between lower dACC activation and positive treatment outcome in emotional tasks with negative stimuli Mixed evidence for association between increased and decreased dACC activation and positive treatment outcome in emotional tasks with negative stimuli
PCC Weak evidence for association between higher PCC activation and positive treatment outcome in emotional tasks with negative stimuli Weak evidence for association between decreased PCC activation and positive treatment outcome in emotional tasks with negative stimuli
dlPFC Weak evidence for association between higher dlPFC activation and positive treatment outcome in cognitive tasks Weak evidence for association between decreased dlPFC activation and positive treatment outcome in cognitive tasks
Insula None reported None reported