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(A) Structure of ACE2 (gray) in complex with Omicron RBD (red) based on the previously published structure 7TN0 (B) Approximate footprint of the ACE2 interaction with SGP-RBD. ACE2 was removed from the image and the SGP-RBD was rotate 60°. Gray RBD residues are located within five angstroms of ACE2 in the bound structure (C) Residues 440K, 478K, 498R, and 505H are shown in blue. The Q493K mutation was not present in this structure.
