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Summary of kinetic data of heparin and SARS-CoV-2 SGP-RBD (WT and mutants) interactions. a
| Interaction | ka (1/MS) | kd (1/S) | Apparent KD (M) |
|---|---|---|---|
| SARS-CoV-2 SGP-RBD WT | 2.3 × 103 (±13) | 1.0 × 10–3 (±3.6 × 10–6) | 4.0 × 10–7 |
| SARS-CoV-2 SGP-RBD Delta | 4.5 × 103 (±33) | 6.1 × 10–4 (±3.5 × 10–6) | 1.4 × 10–7 |
| SARS-CoV-2 SGP-RBD Omicron | 6.0 × 104 (±480) | 6.3 × 10–3 (±3.1 × 10–5) | 1.0 × 10–7 |
The data with (±) in parentheses represent standard deviations (SD) from global fitting of five injections.
