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. 2022 Aug 15;13:978502. doi: 10.3389/fmicb.2022.978502

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Copyright © 2022 Yuan, Yang, Zeng, Li, Fu, Du, Liu, Zhang, Zhou, Chu, Zhang and Zhao.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Synergic interactions of Dimetridazole and Ribavirin with antibiotics. Cell densities of Pseudomonas aeruginosa clinical isolates (A) SIIA-4, (B) SIIA-9, and (C) SIIA-11 cultured in MH broth supplemented with Dimetridazole or Ribavirin and polymyxin B, meropenem, or kanamycin at different combinations. Influences of different combinations of Dimetridazole or Ribavirin and polymyxin B, meropenem, or kanamycin on the growth of (D) SIIA-4, (E) SIIA-9, and (F) SIIA-11 as calculated by the Bliss independence mode. Tiffany blue color indicates antagonistic interaction. Red color indicates synergistic interaction.