Table 1.
Cartilage T1 and T2* Biomarkers Compared Between OA and Control Groups, With Statistical Significance Labeled.
| Cartilage MRI | OA |
Control |
OA vs. Control |
||||
|---|---|---|---|---|---|---|---|
| Maximum | Minimum | Median | Maximum | Minimum | Median | P Value | |
| T1 whole (ms) | |||||||
| Femur | 1,530.00 | 987.00 | 1,220.00 | 1,090.00 | 708.00 | 887.00 | <0.01 |
| Tibia | 1,190.00 | 901.00 | 1,000.00 | 1,090.00 | 682.00 | 789.00 | <0.01 |
| T1_TM (ms) | |||||||
| Femur | 1,770.00 | 883.00 | 1,200.00 | 1,180.00 | 712.00 | 893.00 | <0.01 |
| Tibia | 1,210.00 | 472.00 | 919.00 | 1,250.00 | 347.00 | 613.00 | <0.01 |
| T1_TL (ms) | |||||||
| Femur | 1,530.00 | 873.00 | 1,140.00 | 1,050.00 | 652.00 | 867.00 | <0.01 |
| Tibia | 1,180.00 | 579.00 | 875.00 | 738.00 | 348.00 | 515.00 | <0.01 |
| T1_CM (ms) | |||||||
| Femur | 1,450.00 | 886.00 | 1,070.00 | 1,220.00 | 836.00 | 1,010.00 | 0.16 |
| Tibia | 1,340.00 | 855.00 | 1,080.00 | 1,550.00 | 820.00 | 973.00 | <0.01 |
| T1_CL (ms) | |||||||
| Femur | 1,340.00 | 981.00 | 1,070.00 | 1,230.00 | 639.00 | 913.00 | <0.01 |
| Tibia | 1,140.00 | 929.00 | 1,060.00 | 1,070.00 | 597.00 | 822.00 | <0.01 |
| T1_PM (ms) | |||||||
| Femur | 1,520.00 | 942.00 | 1,320.00 | 1,040.00 | 592.00 | 839.00 | <0.01 |
| Tibia | 1,440.00 | 831.00 | 1,110.00 | 1,210.00 | 697.00 | 856.00 | <0.01 |
| T1_PL (ms) | |||||||
| Femur | 1,440.00 | 1,030.00 | 1,230.00 | 1,060.00 | 705.00 | 853.00 | <0.01 |
| Tibia | 1,330.00 | 840.00 | 1,070.00 | 1,080.00 | 721.00 | 880.00 | <0.01 |
| T2* whole (ms) | |||||||
| Femur | 30.10 | 15.60 | 22.20 | 18.00 | 12.30 | 14.80 | <0.01 |
| Tibia | 21.70 | 10.50 | 13.50 | 12.70 | 8.61 | 10.50 | <0.01 |
| T2*_TM (ms) | |||||||
| Femur | 41.20 | 11.90 | 23.30 | 23.60 | 11.80 | 15.10 | <0.01 |
| Tibia | 14.90 | 7.84 | 11.00 | 14.80 | 7.27 | 9.68 | 0.14 |
| T2*_TL (ms) | |||||||
| Femur | 35.10 | 13.00 | 22.40 | 22.50 | 12.80 | 17.90 | <0.05 |
| Tibia | 25.80 | 6.88 | 9.85 | 15.20 | 7.44 | 10.60 | 0.27 |
| T2*_CM (ms) | |||||||
| Femur | 22.70 | 9.37 | 14.60 | 14.10 | 7.74 | 10.50 | <0.01 |
| Tibia | 19.40 | 7.37 | 10.40 | 12.90 | 7.70 | 9.49 | <0.05 |
| T2*_CL (ms) | |||||||
| Femur | 20.80 | 9.85 | 14.50 | 13.40 | 7.41 | 9.29 | <0.01 |
| Tibia | 17.90 | 7.95 | 10.50 | 10.30 | 5.95 | 7.97 | <0.05 |
| T2*_PM (ms) | |||||||
| Femur | 42.00 | 14.80 | 27.50 | 19.90 | 10.40 | 13.50 | <0.01 |
| Tibia | 28.20 | 11.40 | 18.00 | 15.50 | 8.06 | 11.30 | <0.005 |
| T2*_PL (ms) | |||||||
| Femur | 34.60 | 18.20 | 24.70 | 19.10 | 12.10 | 14.90 | <0.01 |
| Tibia | 27.00 | 9.45 | 14.50 | 15.40 | 8.99 | 11.20 | <0.01 |
MRI = magnetic resonance imaging; OA = osteoarthritis; TM = medial anterior region; TL = lateral anterior region; CM = medial central region; CL = lateral central region; PM = medial posterior region; PL = lateral posterior region.