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. 2022 Aug 15;9:959738. doi: 10.3389/fmolb.2022.959738

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Copyright © 2022 Yin, Li, Zhou, Zhu, Liu, Huang, Shen, Ou, Zhu, Zhang and Liu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effects of the ARNTL expression in AML cancer cell lines in vitro. (A) siARNTL inhibits colony formation in AML cells. (B) siARNTL promoted lipid-ROS production in AML cells. (C). The effect of ferroptosis-related protein expression after the siARNTL treatment. (D). The effect of ferroptosis-related gene expression after the siARNTL treatment. (E). The effect of MDA production after the siARNTL treatment. *p < 0.05, **p < 0.01.