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. 2022 Aug 15;9:955731. doi: 10.3389/fcvm.2022.955731

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Copyright © 2022 Seo, Hong, Youn, Lee, Choi, Kim, Park, Lee, Song, Choi, Hahn, Choi, Gwon, Jeon and Yang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Impact of CAD on longitudinal changes in LVEF and e'. CAD, coronary artery disease; HFpEF, heart failure with preserved ejection fraction; LVEF, left ventricular ejection fraction; e', mitral annulus early diastolic velocity. (A–C) In patients with HFpEF without significant CAD, there was no longitudinal change in EF, whereas in patients with CAD, there was a reduction in LVEF, with multiple patients developing reduced LVEF (<50%, dotted lines). (D–F) The e' was significantly decreased in both HFpEF patients with CAD and without CAD, and there were no significant diffrences in the decline of e' between the two groups.