Table 2.
Echocardiographic and angiographic evaluation.
| HFpEF with CAD (n = 285) | HFpEF without CAD (n = 270) | P-value | |
|---|---|---|---|
| Echocardiography | |||
| Left ventricular end diastolic diameter, mm | 50.9 ± 4.8 | 49.7 ± 4.8 | 0.005 |
| Left ventricular end systolic diameter, mm | 31.6 ± 5.3 | 30.1 ± 4.5 | 0.001 |
| Left ventricular mass index, g/m2 | 106.6 ± 26.5 | 100.7 ± 26.1 | 0.089 |
| Left ventricular ejection fraction, % | 61.8 ± 7.2 | 63.0 ± 6.9 | 0.049 |
| Left atrial volume index, ml/m2 | 38.1 ± 16.0 | 39.5 ± 16.3 | 0.426 |
| Early diastolic mitral inflow velocity, m/s | 0.68 ± 0.21 | 0.69 ± 0.23 | 0.435 |
| Late diastolic mitral inflow velocity, m/s | 0.80 ± 0.21 | 0.73 ± 0.21 | <0.001 |
| Mitral annulus early diastolic velocity, m/s | 0.063 ± 0.019 | 0.066 ± 0.022 | 0.265 |
| Early diastolic velocity of the mitral annulus ratio | 12.1 ± 5.1 | 11.5 ± 4.8 | 0.279 |
| Right ventricular systolic pressure, mm Hg | 33.9 ± 8.9 | 31.6 ± 8.7 | 0.036 |
| Tricuspid annular peak systolic velocity, cm/s | 13.2 ± 2.6 | 12.9 ± 2.8 | 0.411 |
| Angiography | |||
| Extent of coronary artery disease | |||
| 1-vessel disease | 139 (49) | ||
| 2-vessel disease | 82 (29) | ||
| 3-vessel disease | 64 (22) | ||
| Disease territory | |||
| Left main coronary artery | 23 (8.1) | ||
| Left anterior descending artery | 195 (68) | ||
| Left circumflex artery | 133 (47) | ||
| Right coronary artery | 157 (55) | ||
| Complete revascularization | 230 (81) | ||
| SYNTAX score | 11.9 ± 9.6 | ||
| Residual SYNTAX score ≤ 8 | 262 (92) |
Values are presented as mean ± standard deviation or number (%).
CAD, coronary artery disease; HFpEF, heart failure with preserved ejection fraction.
Statistical significance was defined as P < 0.05 by Welch's t-test (continuous variables) or the Chi-square t-test (categorical variables). Bold formatting of values indicates the presence of statistical significance (P < 0.05).