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. 2022 Aug 15;12:905653. doi: 10.3389/fcimb.2022.905653

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Copyright © 2022 Nie, Wang, Huang, Yang, Gong, Feng and Yang

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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(A) The comparison of taxonomic composition between tumor and paracancerous tissue samples. Distribution of relative abundance of microbiome in the tumor tissue and paracancerous tissue of each OSCC subject at the phylum, genus, and species level. Histograms described relative abundances of the (B) top 10 phylum, (C) 10 genera, and (D) top 10 species in the tumor tissue and paracancerous tissue. (E–G) Prevalence of bacterial phylum, genera and species associated with tumor and paracancerous tissue of OSCC subjects. C, tumor tissue; PC, paracancerous tissue. ns, no significance; *P < 0.05, **P < 0.005, ***P < 0.001, ****P < 0.0001.