Table 2.
Altered connectivity with the left aINS in patients with insomnia disorder compared with healthy controls.
| Brain region1 | MNI coordinates (x, y, z) | Number of voxels | Post-hoc p values | |||||
|---|---|---|---|---|---|---|---|---|
| Group-by-stage interaction | Wake | N1 | N2 | N3 | ||||
| Occipital_Mid_L/Temporal_Inf_R | (-30, −84, 22) | 2190 | 41.11 | 0.0021 | 0.96 | 0.0001 | 0.0034 | |
| Occipital_Mid_R | (34, −74, 20) | 841 | 33.83 | 0.0007 | 1.00 | 0.22 | 0.0081 | |
| Frontal_Sup_B | (-8, 14, 62) | 663 | 32.30 | 0.013 | 1.00 | 1.00 | 0.10 | |
| Temporal_Inf_R | (36, −72, −14) | 404 | 24.48 | 0.0004 | 1.00 | 0.0062 | 1.00 | |
| Postcentral_R | (48, −16, 34) | 322 | 28.33 | 0.69 | 0.11 | 0.085 | 0.039 | |
| Group effect | ||||||||
| None | ||||||||
1
N = 33 for the patients, N = 31 for the controls; Abbreviations: Mid, middle; L, left; Inf, inferior; R, right; Sup, superior; B, bilateral; MNI, Montreal Neurological Institute. p values are corrected by Bonferroni correction.