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. 2022 Aug 15;13:901340. doi: 10.3389/fphar.2022.901340

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Copyright © 2022 Wicik, Nowak, Jarosz-Popek, Wolska, Eyileten, Siller-Matula, von Lewinski, Sourij, Filipiak‬ and Postuła.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Most interesting tissues from a clinical point of view are sorted by the potential of being affected by SGLT2 and the first-level SGLT2 interaction network. These lists of tissues were generated according to the SGLT2 level, obtained from (A) The TISSUES 2.0 database expression confidence values and (B) Genotype-Tissue Expression (GTEx) project Transcripts Per Million (TPM) values. In the figure are also present expression levels of SGLT1, which is a co-target for some SGLT2 inhibitors. Legend for both panels is shown in the top right corner of panel (B).