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. 2022 Aug 15;13:901340. doi: 10.3389/fphar.2022.901340

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Copyright © 2022 Wicik, Nowak, Jarosz-Popek, Wolska, Eyileten, Siller-Matula, von Lewinski, Sourij, Filipiak‬ and Postuła.

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Top 10 shortest paths from 50 identified between SGLT2 (SLC2A5) and each key terms-related gene. Genes associated with specific key terms (A–G) have blue labels. The shortest path analysis was performed using the PathLinker Cytoscape app (Paths ranks are marked with pink numbers). Notice that interactions between SGLT2 and SIRT1 had very low ranks for all analyzed key terms, except for mTOR. The thickness of the edges is related to the interaction confidence level obtained from the String database.