Fig. 6.

Total lesion volume measured at 3T and 64mT shows agreement. (A) 3T and 64mT total lesion volume estimates were strongly correlated (Pearson’s correlation, r = 0.89, p < 0.001). However, when compared to y = x there is a clear bias towards over-segmentation at low levels of total lesion volume. (B) A Bland-Altman plot illustrates the level of agreement between 3T and 64mT segmentation volumes (bias −1.6 ml, standard error of measurement = 5.2 ml, 95% limit of agreement −19.0 to 15.9 ml). The Pearson’s correlation (r = 0.74, p < 0.001) in dark blue further indicates over-segmentation at 64mT when lesion volume is low and under-segmentation when lesion volume is high. (For interpretation of the references to colour in this figure legend, the reader is referred to the web version of this article.)