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. 2022 Jul 14;35:103107. doi: 10.1016/j.nicl.2022.103107

Table 2.

Modified Boston criteria.

Clinical data and MRI/CT demonstrating:
Probable CAA
  • -

    Multiple hemorrhages (ICH, CMB) restricted to lobar, cortical, or cortico-subcortical regions (CBL allowed) OR single lobar, cortical, or cortico-subcortical hemorrhage and cSS (focal or disseminated)

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    Age ≥ 55 years

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    Absence of other cause of hemorrhage

Possible CAA
  • -

    Single lobar, cortical, or cortico-subcortical ICH, CMB, or cSS (focal or disseminated)

  • -

    Age ≥ 55 years

  • -

    Absence of other cause of hemorrhage

To classify patients according to the modified Boston criteria non-contrast CT and/or MRI are evaluated. In this table, only the categories without incorporation of histopathological data are shown. CAA = cerebral amyloid angiopathy; CBL = cerebellum; CMB = cerebral microbleed; cSS = cortical superficial siderosis; ICH = intracerebral hemorrhage.