Fig. 1.

Example data for one control (25-year-old female) and one participant with MS (25-year-old female, EDSS 0, disease duration < 1 year). Shown are the mFFE anatomical image used for lesion identification, vertebral level identification and segmentation; the average functional image showing grey/white matter contrast after motion correction; grey matter horns regions of interest in functional space used to derive functional correlations; tissue type segmentations in diffusion space overlaid on a b = 0 image; and FA, RD, AD and MD quantitative maps. A dorsal column lesion in the MS participant is shown with a red arrow, and the corresponding lesion mask in DTI space in red on the segmentation image. (For interpretation of the references to colour in this figure legend, the reader is referred to the web version of this article.)