Fig. 2.

Example of a severely damaged putamen segmentation (left side of the image). A) No apparent evidence of putamen tissue. B) Putamen tissue is successfully segmented. While not evident, navigating through surrounding slices reinforce the selection of this tissue as part of the putamen. C) Putamen tissue and shape clearly visible, although not intact. Dominant hemisphere structure is carefully kept separate from globus pallidus. D) White matter tracts inform the segmentation of both structures in this slice, and all subsequent slices.