Representative mRNA expression and ATP content in mice.A–D, mRNA expression of fatty acid uptake, triglyceride synthesis, do novo lipogenesis, and fatty acid β-oxidation genes in the liver tissues from mice in the chow (14 days), WT-PN (14 days), Ppp2ca-LKO-PN (14 days), and Ad-PP2A-PN (14 days) groups. E, Hepatic adenosine triphosphate (ATP) content for mice in the chow (14 days), WT-PN (14 days), Ppp2ca-LKO-PN (14 days), and Ad-PP2A-PN (14 days) groups. F–G, TG and ATP content of AML12 cells. Some AML12 cells were treated with 2 μM LB-100 (a PP2A inhibitor) or/and 10 μM MK-2206 (an Akt inhibitor) for 24 hours. H, Hepatic ATP content for mice in the WT-PN (14 days), Ad-PP2A-PN (14 days), and Ad-PP2A+SC79 (14 days) groups. The results are expressed as the mean ± standard deviation (n = 5–7). ∗P < .05; ∗∗P < .01; ∗∗∗P < .001.