PP2A-Cα was downregulated in mice and patients with PNAHS.A–B, Western blot analyses and densitometric quantification of the expression levels of various proteins of interest in mice. C, Hepatic mRNA expression levels of the Aα, Aβ, B55α, B55β, B55δ, B56α, B56β, B56γ, and B56δ subunits of PP2A in mice from the chow and PN-14 groups. D, Western blot analyses and densitometric quantification of the expression levels of various proteins in patients with PNAHS and controls. The results are expressed as the mean ± standard deviation (n = 5–7 mice/group, n = 8–10 patients/group). ∗P < .05; ∗∗P < .01; ∗∗∗P < .001.