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Multivariable analysis was adjusted for age, sex, alcohol use, log10-normalized WMH volume, number of lacunes, type of SVD, microbleeds, and total PVS score. WM: white matter; WMH: white matter hyperintensities; CADASIL: cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy; PVS: perivascular spaces.; CVR: cerebrovascular reactivity.
