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. Author manuscript; available in PMC: 2022 Aug 29.
Published in final edited form as: Clin Transplant. 2020 Dec 29;35(2):e14190. doi: 10.1111/ctr.14190

Table 2.

Relationship Between Karnofsky Performance Status and Clinical Outcomes of Patients Listed for SLKT (Cohort 1)

Unadjusted HR Adjusted HR* Unadjusted SHR Adjusted SHR*

Death/deterioration
 Karnofsky A 1 (Ref) 1 (Ref) 1 (Ref) 1 (Ref)
 Karnofsky B 1.36 (1.25–1.49) 1.16 (1.05–1.27) 1.06 (0.97–1.15) 1.06 (0.971.16)
 Karnofsky C 2.93 (2.67–3.23) 1.49 (1.34–1.66) 1.32 (1.21–1.45) 1.15 (1.041.28)

Transplantation
 Karnofsky A 1 (Ref) 1 (Ref) 1 (Ref) 1 (Ref)
 Karnofsky B 1.30 (1.21–1.40) 1.04 (0.97–1.13) 1.14 (1.06–1.22) 0.98 (0.911.05)
 Karnofsky C 2.51 (2.33–2.71) 1.30 (1.19–1.42) 1.56 (1.45–1.67) 1.06 (0.971.15)

Death or transplantation
 Karnofsky A 1 (Ref) 1 (Ref) N/A N/A
 Karnofsky B 1.33 (1.25–1.40) 1.09 (1.03–1.16)
 Karnofsky C 2.67 (2.52–2.84) 1.38 (1.29–1.47)
*

Adjusted for Age, Sex, Race/Ethnicity, Diabetes, MELD, Albumin, Dialysis, ABO Blood type, Ascites, Encephalopathy, Cirrhosis Etiology, HCC, Region, Year of Listing