Figure 5. The intersect of activity in early stage processes and network formation.

Venn diagrams indicate the intersect between chemicals that were active in the early stage process and in the NFA. A chemical was considered active if it was a hit in at least one endpoint in the assay, including cytotoxicity. The early stage processes include: A) NOG (in rat cortical neurons), B) NOG (in human neural cells), or C) synaptogenesis and neurite maturation (in rat cortical cells).