Table 3.
Comparison of the examination findings in Dravet syndrome patients with and without SCN1A variations
Variable | SCN1A-positive (n = 12) | SCN1A-negative (n = 3) | Test | p value |
---|---|---|---|---|
Age of onset of febrile seizure, months (median, range) | 4.75 (3–9) | 5.0 (4–7) | Z = 0.591 | 0.555 |
Age of onset of afebrile seizure, months (median, range) | 6.0 (4–10) | 6.0 (5–8) | Z = 0.221 | 0.825 |
EEG initial abnormalities, % (n) | 50 (6) | 0 (0) | χ2 = 2.500 | 0.229 |
Present focal seizures, % (n) | 25 (3) | 33.3 (1) | χ2 = 0.085 | 1.000 |
Fever-sensitive seizures, % (n) | 83.3 (10) | 66.7 (2) | χ2 = 0.417 | 0.516 |
Vaccination-related seizures, % (n) | 33.3 (4) | 0 (0) | χ2 = 1.364 | 0.516 |
Status epilepticus, % (n) | 25 (3) | 33.3 (1) | χ2 = 0.085 | 1.000 |
EEG, electroencephalogram; Z, Mann-Whitney U-test value. χ2, Fisher's exact test.