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. Author manuscript; available in PMC: 2022 Aug 29.
Published in final edited form as: Oncogene. 2011 Jun 13;31(1):116–127. doi: 10.1038/onc.2011.217

Figure 1.

Figure 1

Identification of transcription factors that regulate BRCA1 expression. (a) Structures of BRCA1 and NRB promoter regions. Two groups of reporter constructs were used in this study. (b) Luciferase activities of BRCA1 reporter constructs in MCF-7 cells. (c) Fold change in luciferase activity of the 0.24-kb construct after transfection of YY1, CSEN, CITED, TRIP4 and HDAC9. Luciferase activity induced by YY1 and TRIP expression reached significant levels over pcDNA mock vector. *Student’s t test, P<0.05.