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. Author manuscript; available in PMC: 2022 Aug 29.
Published in final edited form as: Oncogene. 2011 Jun 13;31(1):116–127. doi: 10.1038/onc.2011.217

Figure 6.

Figure 6

YY1 gene expression in human cancers. (a) Expression levels of YY1 protein in 42 (including 9 metastasis cases) breast cancer and 19 normal breast tissue samples measured by tissue array. YY1 and BRCA1 protein levels were detected by immunohistochemical staining using antibodies against YY1 and BRCA1, and intensity of staining was classified as no, low, medium, high or very high. (b) Immunohistochemical images. The boxed regions (enlarged below) show high levels of YY1 in normal epithelium and lower levels in cancers. Scale bars = 100 μm. (c) YY1 and BRCA1 protein levels in 46 human sporadic breast cancers. These cancer samples were reported previously (Man et al., 2005). Intensity of YY1 and BRCA1 staining of these cancers showed a positive correlation. Representative images with low and high expression of BRCA1 and YY1 were shown.