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. 2022 Jul 6;4:ojac061. doi: 10.1093/asjof/ojac061

Table 3.

Comparison of AEs Among 3 Skin Resurfacing Studies

AE type AEs this study (n = 301) HPDR
3 passes, 35% power
AEs, Holcomb et al13 (n = 55) HPDR
1 pass, 20% power
AEs, Weniger et al23  
(n = 472)
Erbium-YAG laser
deep resurfacing
Acne/milia 1 5+ Unknown
Hyperpigmentation 3 8 Unknown
Hypertrophic scarring 1 2 7a
Hypopigmentation 0 0 6a
Prolonged erythema 10 0 70a
Slow healing 1 4 Unknown

AEs observed in this study compared with similar AEs in two recent facial skin resurfacing studies including HPDR (lower energy, single pass treatment; Holcomb et al) and dual mode erbium YAG laser skin resurfacing (Weniger et al23).

aNumber of patients determined based on percentage observed and total patients treated. AE, adverse event; HPDR, helium plasma dermal resurfacing.