Table 2.
Patient clinical and pathologic characteristics
| Characteristics | Total (n = 166) | Age 75–79 (n = 130) | Age ≥ 80 (n = 36) | P value |
|---|---|---|---|---|
| Age at surgery (median) | 77 (75–89) | 76 (75–79) | 82 (80–89) | < 0.001 |
| Gender, n (%) | 0.907 | |||
| Man | 112 (67.5) | 88 (67.7) | 24 (66.7) | |
| Woman | 54 (32.5) | 42 (32.3) | 12 (33.3) | |
| BMI (mean ± SD) | 21.5 ± 1.8 | 21.3 ± 2.5 | 21.6 ± 1.6 | 0.536 |
| KPS score < 80, n (%) | 23 (13.9) | 15 (11.5) | 8 (22.2) | 0.016 |
| Number of underlying diseases, n (%) | 0.019 | |||
| < 2 | 106 (63.9) | 89 (68.5) | 17 (47.2) | |
| ≥ 2 | 60 (36.1) | 41 (31.5) | 19 (52.8) | |
| Presenting symptom, n (%) | 25 (15.1) | 19 (14.6) | 6 (16.7) | 0.761 |
| Baseline eGFR (ml/min) | 70.5 ± 9.7 | 72.1 ± 5.9 | 63.1 ± 6.4 | < 0.001 |
| Postoperative eGFR (ml/min) | 61.7 ± 8.8 | 63.3 ± 5.4 | 52.1 ± 5.6 | < 0.001 |
| Tumor size (median) | 5.1 (1.8–13) | 5.0 (2.5–12.6) | 5.3 | 0.314 |
| Tumor location, n (%) | 0.831 | |||
| Left | 85 (51.2) | 66 (50.8) | 19 (52.8) | |
| Right | 83 (48.8) | 64 (49.2) | 17 (47.2) | |
| Surgery procedure, n (%) | 0.772 | |||
| Open | 12 (7.2) | 9 (6.9) | 3 (8.3) | |
| Laparoscopic | 154 (92.8) | 121 (93.1) | 33 (91.7) | |
| Surgery method | 0.097 | |||
| Radical | 115 (69.3) | 86 (66.2) | 29 (80.6) | |
| Partial | 51 (30.7) | 44 (33.8) | 7 (19.4) | |
| RENAL score (partial) | 0.471 | |||
| ≤ 9 | 39 (76.5) | 33 (75.0) | 6 (85.7) | |
| > 9 | 12 (23.5) | 11 (25.0) | 1 (14.3) | |
| Pathological type | 0.960 | |||
| Clear cell carcinoma | 144 (86.7) | 113 (86.9) | 31 (86.1) | |
| Papillary | 11 (6.6) | 8 (6.2) | 3 (8.3) | |
| Chromophobe | 6 (3.6) | 5 (3.8) | 1 (2.8) | |
| Others | 5 (3.0) | 4 (3.1) | 1 (2.8) | |
| ISUP grade, n (%) | 0.595 | |||
| Low grade ≤ 2 | 95 (57.2) | 73 (56.2) | 22 (61.1) | |
| High grade ≥ 3 | 71 (42.8) | 57 (43.8) | 14 (38.9) | |
| Tumor necrosis, n (%) | 29 (17.5) | 21 (16.2) | 8 (22.2) | 0.724 |
| Sarcomatoid differentiation, n (%) | 26 (15.7) | 19 (14.6) | 7 (19.4) | 0.481 |
| Lymph node metastasis, n (%) | 8 (4.8) | 6 (4.6) | 2 (5.6) | 0.816 |
| Pathological T stage, n (%) | 0.794 | |||
| T1 | 134 (80.7) | 105 (80.8) | 29 (80.6) | |
| T2 | 21 (12.7) | 17 (13.1) | 4 (11.1) | |
| T3 | 9 (5.4) | 7 (5.4) | 2 (5.6) | |
| T4 | 2 (1.2) | 1 (0.8) | 1 (2.8) |