Table 2.
The results of causal analysis of human blood metabolites (exposure) and pulmonary embolism (outcome)
| Exposure group | Number of SNP | Analytical method | Beta | SE | 95%CI | P |
|---|---|---|---|---|---|---|
| 1-stearoylglycerophosphoethanolamine | 1 | Wald ratio | −0.009597 | 0.007869 | (−0.0250, 0.0059) | 0.2226 |
| X-12100--hydroxytryptophan | 2 | IVW | −0.0294 | 0.01056 | (−0.0087, − 0.0500) | 0.005349 |
| X-11412 | 1 | Wald ratio | −0.01947 | 0.0178 | (−0.0543,0.0154) | 0.274 |
| X-12029 | 1 | NA | ||||
| N1-methyladenosine | 1 | Wald ratio | −0.006814 | 0.0306 | (−0.0668,0.0532 | 0.8238 |
| valine | 1 | Wald ratio | −0.02911 | 0.02328 | (−0.0747,0.0165 | 0.211 |
Tests were considered statistically significant at P values < 0.05. The MR base platform (http://app.mrbase.org/) was used for MR analyses