Fig. 3.

Proportion of patients experiencing downward shifts in A) HIT-6 severity categories and B) MIDAS severity grades during 12 weeks of treatment. HIT-6, 6-item Headache Impact Test; MIDAS, Migraine Disability Assessment. n values shown are the number of patients with data available for analysis of shift in disability severity category in HIT-6 or MIDAS scores at the end of treatment. Total proportion of patients with a downward shift of 1, 2, or 3 categories or grades (as shown at the top of each bar) may differ from the sum of the proportions of patients with downward shifts of 1, 2, or 3 categories or grades due to rounding. ^aP < 0.0001 versus placebo